Allergan, Inc. to Acquire Privately Held Dermatologic Company, Vicept
Therapeutics
July 19, 2011
- Vicept Therapeutics successfully completed a
Phase II clinical development program of a novel topical cream for the
treatment of the erythema of rosacea
- Acquisition strategically
aligns with Allergan's leadership position in medical dermatology and its
pursuit of innovative therapies to address unmet dermatologic needs
MALVERN, Pa. & IRVINE, Calif.--(BUSINESS WIRE)-- Vicept Therapeutics
and Allergan, Inc. (NYSE:AGN) today announced that they have entered into
a definitive agreement for Allergan to acquire all of the outstanding
shares and assets of the privately-held dermatology company. The
agreement, estimated to close in the third quarter of 2011, includes a $75
million cash up-front payment by Allergan plus up to an aggregate of $200
million in payments payable by Allergan contingent upon achieving certain
future development and regulatory milestones plus additional payments
contingent upon acquired products achieving certain sales milestones.
Founded in 2009 and backed by Vivo Ventures, Fidelity Biosciences and
Sofinnova Ventures, Vicept Therapeutics' lead investigational product,
V-101, is a topical cream for the treatment of the erythema (redness)
associated with rosacea that has achieved positive results in two
randomized, placebo-controlled Phase II studies.
"The two Phase II
studies demonstrated the clinical potential of our lead product V-101 in
Type I rosacea (Erythematous Rosacea), a dermatological problem for which
there currently is no approved therapy," said Dr. Neal Walker, President
and CEO of Vicept. "We believe Allergan is the best company to complete
the development and make the therapy available to the clinical community
and their patients, fulfilling our shared mission."
"The
acquisition of Vicept Therapeutics will further enhance our dermatology
research and development pipeline, and matches our corporate strategy and
long-standing commitment to patients suffering from skin disorders," said
Scott M. Whitcup, M.D., Executive Vice President, Chief Scientific Officer
of Allergan. "We look forward to potentially providing a new treatment
option to physicians and their patients suffering from this often
burdensome condition."
Steve Tullman, Executive Chairman of Vicept
added, "The progress Vicept has made was truly a team effort with strong
support from an excellent investor syndicate led by Albert Cha, M.D., PhD
from Vivo Ventures. Vicept is very pleased to reach this agreement with
Allergan, an outstanding global company with a long track record in
dermatology, who can leverage the full value of our rosacea program with
its significant global development and commercialization resources.
Leerink Swann, LLC advised the Board of Directors of Vicept in their
review of strategic alternatives."
About Rosacea
Rosacea
is a common, chronic skin disorder that affects over 15 million Americans
and over 45 million people worldwide.1 Erythematotelenagietic rosacea
(ETR), Type I, is the most commonly encountered subtype, and is most
characterized by frequent episodes of transient facial erythema (flushing)
and non-transient, or persistent, erythema. It may also be accompanied by
facial edema, burning, or stinging, and sensitivity of the skin and
intolerance to topically applied products is common. Rosacea remains a
disorder of uncertain etiology and pathogenesis, though the flushing and
erythema of ETR are theorized to arise from an abnormal response of the
cutaneous blood vessels of the face to neurological, hormonal, thermal,
topical, or other stimuli, resulting in an abnormal dilation of facial
blood vessels. There is currently no approved topical therapy for the
treatment of ETR.
About Vicept Therapeutics Vicept
Therapeutics, Inc. is a privately held specialty pharmaceutical company
with a mission to develop the first effective topically applied therapy
directed toward the erythema of rosacea and other disorders characterized
by redness and or flushing of the skin. The Company is also pursuing the
development of topical agents for the treatment and prevention of a number
of medical and cosmetic indications including bruising of the skin. Visit
www.vicepttx.com for more information.
About Allergan, Inc.
Allergan, Inc. is a multi-specialty health care company established 60
years ago with a commitment to uncover the best of science and develop and
deliver innovative and meaningful treatments to help people reach their
life's potential. Today, we have more than 9,000 highly dedicated and
talented employees, global marketing and sales capabilities with a
presence in more than 100 countries, a rich and ever-evolving portfolio of
pharmaceuticals, biologics, medical devices and over-the-counter consumer
products, and state-of-the-art resources in R&D, manufacturing and safety
surveillance that help millions of patients see more clearly, move more
freely and express themselves more fully. From our beginnings as an eye
care company to our focus today on several medical specialties, including
ophthalmology, neurosciences, obesity, urologics, medical aesthetics and
dermatology, Allergan is proud to celebrate 60 years of medical advances
and proud to support the patients and physicians who rely on our products
and the employees and communities in which we live and work.
Allergan Forward-Looking Statements This press release contains
"forward-looking statements," including, but not limited to, the
statements by Drs. Whitcup and Walker, and Mr. Tullman and other
statements regarding the development of V-101 as well as the safety,
effectiveness, approvals, adverse events and market potential of V-101.
These statements are based on current expectations of future events. If
underlying assumptions prove inaccurate or unknown risks or uncertainties
materialize, actual results could vary materially from Allergan's
expectations and projections. Risks and uncertainties include, among other
things, general industry and pharmaceutical market conditions;
technological advances and patents attained by competitors; challenges
inherent in the research and development and regulatory processes;
challenges related to product marketing, such as the unpredictability of
market acceptance for new products and/or the acceptance of new
indications for such products; inconsistency of treatment results among
patients; general economic conditions; and governmental laws and
regulations affecting domestic and foreign operations. Allergan expressly
disclaims any intent or obligation to update these forward-looking
statements except as required by law. Additional information concerning
the above referenced risk factors and other risk factors can be found in
Allergan's public periodic filings with the Securities and Exchange
Commission, including the discussion under the heading "Risk Factors" in
Allergan's 2010 Annual Report on Form 10-K and subsequent Quarterly
Reports on Form 10-Q. Additional information about Allergan is available
at www.allergan.com or you can contact the Allergan Investor Relations
Department by calling 714-246-4636.
1 Crawford GH, Pelle MT, James
WD. Rosacea, I: etiology, pathogenesis, and subtype classification. J Am
Acad Dermatol. 2004;51(3):327-341.
Vicept Media ContactMike Beyer, Sam Brown, Inc.
773-463-4211
beyer @sambrown.com
Allergan Media/IR ContactJim Hindman
(714) 246-4636 (investors)
Joann Bradley (714) 246-4766 (investors)
David Nakasone (714) 246-6376 (investors)
Caroline Van Hove (714)
246-5134 (media)